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Brefeldin A

CAS No. 20350-15-6

Brefeldin A( Ascotoxin | BFA | Cyanein | Decumbin | Nectrolide | NSC 56310 | Synergisidin )

Catalog No. M13166 CAS No. 20350-15-6

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces Y cell differentiation and apoptosis.

Purity : >98% (HPLC)

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Biological Information

Product Name

Brefeldin A
Note

Research use only, not for human use.
Brief Description

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces Y cell differentiation and apoptosis.
Description

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces Y cell differentiation and apoptosis.
In Vitro

——
In Vivo

——
Synonyms

Ascotoxin | BFA | Cyanein | Decumbin | Nectrolide | NSC 56310 | Synergisidin
Pathway

Endocrinology/Hormones
Target

ATPase
Recptor

ATPase (HCT 116)
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

20350-15-6
Formula Weight

280.36
Molecular Formula

C16H24O4
Purity

>98% (HPLC)
Solubility

DMSO: 4 mg/mL (14.26 mM)
SMILES

C[C@H]1CCC/C=C/[C@@H]2C[C@@H](C[C@H]2[C@@H](/C=C/C(=O)O1)O)O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zhu JW, et al. Bioorg Med Chem. 2000, 8(2), 455-463.

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